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The Chemistry of Antitumour Platinum Complexes

Anastasiya Ivanovna Stetsenko 1
Anastasiya Ivanovna Stetsenko
, 
M A Presnov 2
M A Presnov
, 
A L Konovalova 2
A L Konovalova
1 Leningrad Institute of Chemical Technology
2 All-Union Cancer Research Center, Academy of Medical Sciences of the USSR, Moscow
10.1070/RC1981v050n04ABEH002605
Published 30 November 1980
Communication , Volume 50, Issue 4, 353-367
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Stetsenko A. I., Presnov M. A., Konovalova A. L. The Chemistry of Antitumour Platinum Complexes // Russian Chemical Reviews. 1981. Vol. 50. No. 4. pp. 353-367.
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Stetsenko A. I., Presnov M. A., Konovalova A. L. The Chemistry of Antitumour Platinum Complexes // Russian Chemical Reviews. 1981. Vol. 50. No. 4. pp. 353-367.
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TY - JOUR
DO - 10.1070/RC1981v050n04ABEH002605
UR - https://rcr.colab.ws/publications/10.1070/RC1981v050n04ABEH002605
TI - The Chemistry of Antitumour Platinum Complexes
T2 - Russian Chemical Reviews
AU - Stetsenko, Anastasiya Ivanovna
AU - Presnov, M A
AU - Konovalova, A L
PY - 1981
DA - 1980/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 353-367
IS - 4
VL - 50
ER -
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@article{1981_Stetsenko,
author = {Anastasiya Ivanovna Stetsenko and M A Presnov and A L Konovalova},
title = {The Chemistry of Antitumour Platinum Complexes},
journal = {Russian Chemical Reviews},
year = {1981},
volume = {50},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RC1981v050n04ABEH002605},
number = {4},
pages = {353--367},
doi = {10.1070/RC1981v050n04ABEH002605}
}
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Stetsenko, Anastasiya Ivanovna, et al. “The Chemistry of Antitumour Platinum Complexes.” Russian Chemical Reviews, vol. 50, no. 4, Nov. 1981, pp. 353-367. https://rcr.colab.ws/publications/10.1070/RC1981v050n04ABEH002605.
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Abstract

The antitumour activities of platinum complexes have been characterised in connection with their composition, structure, and properties. A relation has been established between the antiblastoma properties of platinum complexes and the charge and nature of neutral and acido-ligands, the geometrical configuration, and the degree of oxidation of the central atom. Hypotheses are put forward concerning the mechanism of the antitumour activity of platinum complexes. The prospects for the application of platinum and other platinum metal complexes in tumour chemotherapy are assessed.
The bibliography includes 131 references.