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Phosphorylated Derivatives of Alkaloids and Nitrogen-containing Heterocycles – Cholinesterase Inhibitors

Abid Sadykovich Sadykov 1
Abid Sadykovich Sadykov
, 
Davranbek Nigmanovich Dalimov 1
Davranbek Nigmanovich Dalimov
, 
Nikolai Nikolaevich Godovikov 2
Nikolai Nikolaevich Godovikov
1 Institute of Bioorganic Chemistry UzSSR, Tashkent
2 A. N. Nesmeyanov Institute of Organoelement Compounds, USSR Academy of Sciences, Moscow
10.1070/RC1983v052n10ABEH002895
Published 30 November 1982
Communication , Volume 52, Issue 10, 918-930
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Sadykov A. S., Dalimov D. N., Godovikov N. N. Phosphorylated Derivatives of Alkaloids and Nitrogen-containing Heterocycles – Cholinesterase Inhibitors // Russian Chemical Reviews. 1983. Vol. 52. No. 10. pp. 918-930.
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Sadykov A. S., Dalimov D. N., Godovikov N. N. Phosphorylated Derivatives of Alkaloids and Nitrogen-containing Heterocycles – Cholinesterase Inhibitors // Russian Chemical Reviews. 1983. Vol. 52. No. 10. pp. 918-930.
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TY - JOUR
DO - 10.1070/RC1983v052n10ABEH002895
UR - https://rcr.colab.ws/publications/10.1070/RC1983v052n10ABEH002895
TI - Phosphorylated Derivatives of Alkaloids and Nitrogen-containing Heterocycles – Cholinesterase Inhibitors
T2 - Russian Chemical Reviews
AU - Sadykov, Abid Sadykovich
AU - Dalimov, Davranbek Nigmanovich
AU - Godovikov, Nikolai Nikolaevich
PY - 1983
DA - 1982/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 918-930
IS - 10
VL - 52
ER -
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@article{1983_Sadykov,
author = {Abid Sadykovich Sadykov and Davranbek Nigmanovich Dalimov and Nikolai Nikolaevich Godovikov},
title = {Phosphorylated Derivatives of Alkaloids and Nitrogen-containing Heterocycles – Cholinesterase Inhibitors},
journal = {Russian Chemical Reviews},
year = {1983},
volume = {52},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RC1983v052n10ABEH002895},
number = {10},
pages = {918--930},
doi = {10.1070/RC1983v052n10ABEH002895}
}
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Sadykov, Abid Sadykovich, et al. “Phosphorylated Derivatives of Alkaloids and Nitrogen-containing Heterocycles – Cholinesterase Inhibitors.” Russian Chemical Reviews, vol. 52, no. 10, Nov. 1983, pp. 918-930. https://rcr.colab.ws/publications/10.1070/RC1983v052n10ABEH002895.
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Abstract

The review deals with the synthesis and anticholinesterase activities of phosphorylated derivatives of certain alkaloids and nitrogen-containing heterocycles. It is shown that the conformational properties of the alkaloid and nitrogen-containing heterocycle residues in the composition of the organophosphorus inhibitor (OPI) molecule play an important role in the inhibition of the catalytic activity of cholinesterases. The type of inhibition of cholinesterases also varies as a function of chemical structure.
The bibliography includes 45 references.