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Intermediate Compounds and Intermediate Reactions in the Synthesis of Oligonucleotides

Valentina Filippovna Zarytova 1
Valentina Filippovna Zarytova
, 
Dmitrii Georgievich Knorre 1
Dmitrii Georgievich Knorre
1 Novosibirsk Institute of Organic Chemistry of USSR Academy of Sciences, Siberian Branch
10.1070/RC1985v054n02ABEH003015
Published 30 November 1984
Communication , Volume 54, Issue 2, 185-198
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Zarytova V. F., Knorre D. G. Intermediate Compounds and Intermediate Reactions in the Synthesis of Oligonucleotides // Russian Chemical Reviews. 1985. Vol. 54. No. 2. pp. 185-198.
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Zarytova V. F., Knorre D. G. Intermediate Compounds and Intermediate Reactions in the Synthesis of Oligonucleotides // Russian Chemical Reviews. 1985. Vol. 54. No. 2. pp. 185-198.
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TY - JOUR
DO - 10.1070/RC1985v054n02ABEH003015
UR - https://rcr.colab.ws/publications/10.1070/RC1985v054n02ABEH003015
TI - Intermediate Compounds and Intermediate Reactions in the Synthesis of Oligonucleotides
T2 - Russian Chemical Reviews
AU - Zarytova, Valentina Filippovna
AU - Knorre, Dmitrii Georgievich
PY - 1985
DA - 1984/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 185-198
IS - 2
VL - 54
ER -
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@article{1985_Zarytova,
author = {Valentina Filippovna Zarytova and Dmitrii Georgievich Knorre},
title = {Intermediate Compounds and Intermediate Reactions in the Synthesis of Oligonucleotides},
journal = {Russian Chemical Reviews},
year = {1985},
volume = {54},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RC1985v054n02ABEH003015},
number = {2},
pages = {185--198},
doi = {10.1070/RC1985v054n02ABEH003015}
}
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Zarytova, Valentina Filippovna, and Dmitrii Georgievich Knorre. “Intermediate Compounds and Intermediate Reactions in the Synthesis of Oligonucleotides.” Russian Chemical Reviews, vol. 54, no. 2, Nov. 1985, pp. 185-198. https://rcr.colab.ws/publications/10.1070/RC1985v054n02ABEH003015.
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Abstract

The principal features of the phosphorylation of nucleosides and other alcohols by phosphoric acid monoesters and diesters in the presence of the most widely used condensing agents (arenesulphonyl chlorides, arenesulphonyl azolides, carbodiimides, mixtures of arenesulphonyl chlorides with azoles and pyridines) are described. Data concerning the intermediate compounds and intermediate reactions in the oligonucleotides synthesis as well as model processes, obtained mainly with the aid of 31P NMR, are discussed.
The bibliography includes 67 references.