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'Smart' polymers in biotechnology and medicine

Igor Yur'evich Galaev 1
Igor Yur'evich Galaev
1 Department of Biotechnology, Center for Chemistry and Chemical Engineering, Lund University, Sweden
Published 30 November 1994
Communication , Volume 64, Issue 5, 471-489
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Galaev I. Y. 'Smart' polymers in biotechnology and medicine // Russian Chemical Reviews. 1995. Vol. 64. No. 5. pp. 471-489.
GOST all authors (up to 50)
Galaev I. Y. 'Smart' polymers in biotechnology and medicine // Russian Chemical Reviews. 1995. Vol. 64. No. 5. pp. 471-489.
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TY - JOUR
DO - 10.1070/RC1995v064n05ABEH000161
UR - https://rcr.colab.ws/publications/10.1070/RC1995v064n05ABEH000161
TI - 'Smart' polymers in biotechnology and medicine
T2 - Russian Chemical Reviews
AU - Galaev, Igor Yur'evich
PY - 1995
DA - 1994/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 471-489
IS - 5
VL - 64
ER -
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@article{1995_Galaev,
author = {Igor Yur'evich Galaev},
title = {'Smart' polymers in biotechnology and medicine},
journal = {Russian Chemical Reviews},
year = {1995},
volume = {64},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RC1995v064n05ABEH000161},
number = {5},
pages = {471--489},
doi = {10.1070/RC1995v064n05ABEH000161}
}
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Galaev, Igor Yur'evich. “'Smart' polymers in biotechnology and medicine.” Russian Chemical Reviews, vol. 64, no. 5, Nov. 1995, pp. 471-489. https://rcr.colab.ws/publications/10.1070/RC1995v064n05ABEH000161.
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Abstract

'Smart' water-soluble polymers and hydrogels are capable of responding reversibly to slight changes in the properties of the medium (pH, temperature, ionic strength, the presence of certain substances, illumination, electric field), the response of the system being readily seen with the naked eye (the formation of a new phase in a hitherto homogeneous solution, sudden swelling or contraction of the hydrogel). The properties of such polymers and hydrogels are examined. The use of 'smart' polymers and hydrogels for the concentration of protein solutions and the dehydration of suspensions, for the creation of membranes with a controllable permeability, for the isolation and purification of biomolecules, for the immobilisation of biocatalysts, and for the creation of sensor systems and systems for the controlled release of medicinal drugs is discussed. The bibliography includes 261 references.

References

1.
Nickel-Titanium Memory Metal: A "Smart" Material Exhibiting a Solid-State Phase Change and Superelasticity
Gisser K.R., Geselbracht M.J., Cappellari A., Hunsberger L., Ellis A.B., Perepezko J., Lisensky G.C.
Journal of Chemical Education , 1994
2.
Mechanochemical Engines
STEINBERG I.Z., OPLATKA A., KATCHALSKY A.
Nature , 1966
4.
Synthetic gels on the move
Kajiwara K., Ross-Murphy S.B.
Nature , 1992
5.
5
A. A. Krasnovskii
Dokl. Akad. Nauk SSSR , 1953
7.
7
E. Rabinowitch
"Photosynthesis" , 1956
8.
Phase Transitions in Ionic Gels
Tanaka T., Fillmore D., Sun S., Nishio I., Swislow G., Shah A.
Physical Review Letters , 1980
9.
Volume transition in a gel driven by hydrogen bonding
Ilmain F., Tanaka T., Kokufuta E.
Nature , 1991
10.
Volume‐phase transitions of ionized N‐isopropylacrylamide gels
Hirotsu S., Hirokawa Y., Tanaka T.
Journal of Chemical Physics , 1987
11.
Swelling behavior of amphoteric gel and the volume phase transition
Katayama S., Myoga A., Akahori Y.
The Journal of Physical Chemistry , 1992
13.
Phase transition of positively ionized gels
Hirokawa Y., Tanaka T., Sato E.
Macromolecules , 1985
14.
Phase transition of a cationic gel
Katayama S., Ohata A.
Macromolecules , 1985
15.
Salt effects on the phase transition of ionic gels
Ohmine I., Tanaka T.
Journal of Chemical Physics , 1982
17.
Swelling behavior of hyaluronic acid gels
Shah C.B., Barnett S.M.
Journal of Applied Polymer Science , 1992
22.
Effect of Additives on the Clouding Behavior of an Ethylene Oxide-Propylene Oxide Block Copolymer in Aqueous Solution
Pandya K., Lad K., Bahadur P.
Journal of Macromolecular Science - Pure and Applied Chemistry , 1993
24.
Smart ligands that regulate homogeneously catalyzed reactions
Bergbreiter D.E., Zhang L., Mariagnanam V.M.
Journal of the American Chemical Society , 1993
27.
27
A. A. Krasnovskii
Biofizika , 1956
29.
Soluble-insoluble complex of trypsin immobilized on acrolein-acrylic acid copolymer
Van Leemputten E., Horisberger M.
Biotechnology and Bioengineering , 1976
30.
30
V. B. Evstigneev
Dokl. Akad. Nauk SSSR , 1954
31.
THE AFFINITY PRECIPITATION TECHNIQUE.
Schneider M., Guillot C., Lamy B.
Annals of the New York Academy of Sciences , 1981
32.
32
A. A. Krasnovskii
Dokl. Akad. Nauk SSSR , 1952
33.
33
M. B. Neiman
"Issledovanie Mekhanizma Okisleniya Butana" (Research on the Mechanism of the Oxidation of Butane) , 1939
34.
Enzyme‐synthetic polyampholyte systems
Dupommier A., Merle-Aubry L., Merle Y., Sélégny E.
Die Makromolekulare Chemie , 1986
35.
Collapse of Gels in an Electric Field
Tanaka T., Nishio I., Sun S., Ueno-Nishio S.
Science , 1982
36.
Reversible volume change of microparticles in an electric field
Kishi R., Osada Y.
Journal of the Chemical Society Faraday Transactions 1 Physical Chemistry in Condensed Phases , 1989
37.
37
L. M. Kosobutskaya
Dokl. Akad. Nauk SSSR , 1950
38.
Biodegradable and pH-sensitive hydrogels: Synthesis by crosslinking of N,N-dimethylacrylamide copolymer precursors
Yeh P., Kope??ková P., Kope??ek J.
Journal of Polymer Science, Part A: Polymer Chemistry , 1994
39.
39
V. F. Gachkovskii
Biofizika , 1959
40.
40
A. A. Krasnovskii
Biofizika , 1960
41.
41
A. A. Krasnovskii
Dokl. Akad. Nauk SSSR , 1950
44.
Thermoselective permeation from a polymer-grafted capsule membrane
Okahata Y., Noguchi H., Seki T.
Macromolecules , 1986
47.
Solution Properties of Poly(N-isopropylacrylamide) in Water
Kubota K., Fujishige S., Ando I.
Polymer Journal , 1990
50.
50
G. Glacomello
Gazzetta. , 1935
55.
Temperature-responsive characteristics of N-isopropylacrylamide-grafted polymer films prepared by photografting
Kubota H., Nagaoka N., Katakai R., Yoshida M., Omichi H., Hata Y.
Journal of Applied Polymer Science , 1994
56.
56
T. Iasui
Bull. Chem. Soc. Japan. , 1935
57.
57
R. Livingston
"Research in Photosynthesis" , 1957
58.
A Synthetic Hydrogel with Thermoreversible Gelation. I. Preparation and Rheological Properties
Yoshioka H., Mikami M., Mori Y., Tsuchida E.
Journal of Macromolecular Science - Pure and Applied Chemistry , 1994
60.
Solution Properties of Poly(N-isopropylacrylamide)
Heskins M., Guillet J.E.
Journal of Macromolecular Science Part A - Chemistry , 1968
62.
Single-chain transition of poly(N-isopropylacrylamide) in water
Kubota K., Fujishige S., Ando I.
The Journal of Physical Chemistry , 1990
64.
Coil-globule transition of poly(N-isopropylacrylamide): a study of segment mobility by fluorescence depolarization
67.
Stimuli sensitive polymers for drug delivery systems
Kwon I.C., Bae Y.H., Okano T., Kim S.W., Berner B.
Makromolekulare Chemie Macromolecular Symposia , 1990
70.
Interaction of poly(N-isopropylacrylamide) with perfluorooctanoic acid in aqueous solution
Schild H.G., Tirrell D.A.
Makromolekulare Chemie Macromolecular Symposia , 1992
72.
Effect of polyelectrolytes on the lower critical solution temperature of ionizable, thermosensitive polymers
Feil H., Bae Y.H., Feijen J., Kim S.W.
Die Makromolekulare Chemie Rapid Communications , 1993
73.
Adsorption of poly(N-isopropylacrylamide) on silica surfaces
Tanahashi T., Kawaguchi M., Honda T., Takahashi A.
Macromolecules , 1994
74.
74
F. F. Litvin
Uspekhi Fiz. Nauk , 1960
75.
Effect of polymeric surfactants on the cloud point of poly(N-isopropylacrylamide)
Cho C.S., Jung J.H., Sung Y.K., Lee Y.M.
Macromolecular Rapid Communications , 1994
76.
Cononsolvency in mixed aqueous solutions of poly(N-isopropylacrylamide)
Schild H.G., Muthukumar M., Tirrell D.A.
Macromolecules , 1991
77.
Synthesis of poly(N-isopropylacrylamide) hydrogels by radiation polymerization and crosslinking
Nagaoka N., Safrani A., Yoshida M., Omichi H., Kubota H., Katakai R.
Macromolecules , 1993
78.
Synthesis and characterization of pH- and/or temperature-sensitive hydrogels
Park T.G., Hoffman A.S.
Journal of Applied Polymer Science , 1992
80.
Swelling equilibria for weakly ionizable, temperature-sensitive hydrogels
Beltran S., Baker J.P., Hooper H.H., Blanch H.W., Prausnitz J.M.
Macromolecules , 1991
81.
Synthesis and characterization of thermally reversible macroporous poly(N-isopropylacrylamide) hydrogels
Wu X.S., Hoffman A.S., Yager P.
Journal of Polymer Science, Part A: Polymer Chemistry , 1992
82.
Microspheres prepared with a temperature-responsive macromonomer
Takeuchi S., Oike M., Kowitz C., Shimasaki C., Hasegawa K., Kitano H.
Die Makromolekulare Chemie , 1993
85.
85
A. A. Krasnovskii
Dokl. Akad. Nauk SSSR , 1947
86.
Thermal analysis of the volume phase transition with N-isopropylacrylamide gels
Otake K., Inomata H., Konno M., Saito S.
Macromolecules , 1990
87.
Phase transition of submicron gel beads
Hirose Y., Amiya T., Hirokawa Y., Tanaka T.
Macromolecules , 1987
89.
Swelling behavior of N-isopropylacrylamide-based amphoteric gels
Wada N., Yagi Y., Inomata H., Saito S.
Journal of Polymer Science, Part A: Polymer Chemistry , 1993
90.
Solubility parameter of an N-isopropylacrylamide gel
Yagi Y., Inomata H., Saito S.
Macromolecules , 1992
91.
The temperature-controlled flocculation of crosslinked latex particles
Snowden M.J., Vincent B.
Journal of the Chemical Society Chemical Communications , 1992
92.
Deswelling characteristics of poly(N-isopropylacrylamide) hydrogel
Park T.G., Hoffman A.S.
Journal of Applied Polymer Science , 1994
93.
Phase transition of N-substituted acrylamide gels
Inomata H., Goto S., Saito S.
Macromolecules , 1990
94.
Kinetics of discontinuous volume–phase transition of gels
Sato Matsuo E., Tanaka T.
Journal of Chemical Physics , 1988
95.
A new model for the thermally induced volume phase transition of gels
Otake K., Inomata H., Konno M., Saito S.
Journal of Chemical Physics , 1989
96.
Poly(N-isopropylacrylamide) Films at the Air-Water Interface
Kawaguchi M., Saito W., Kato T.
Macromolecules , 1994
99.
Temperature dependence of swelling of crosslinked poly(N,N′-alkyl substituted acrylamides) in water
Bae Y.H., Okano T., Kim S.W.
Journal of Polymer Science, Part B: Polymer Physics , 1990
101.
Reentrant phase transition in acrylamide-derivative copolymer gels
Katayama S., Hirokawa Y., Tanaka T.
Macromolecules , 1984
103.
Effects of surfactants on the phase transition of poly(N-isopropylacrylamide) gel
Kokufuta E., Zhang Y.Q., Tanaka T., Mamada A.
Macromolecules , 1993
104.
Reentrant phase transition of N‐isopropylacrylamide gels in mixed solvents
Amiya T., Hirokawa Y., Hirose Y., Li Y., Tanaka T.
Journal of Chemical Physics , 1987
106.
Swelling behaviors of poly(N-isopropylacrylamide) gel in poly(ethylene glycol)-water mixtures
Ishidao T., Akagi M., Sugimoto H., Iwai Y., Arai Y.
Macromolecules , 1993
108.
Non-radiative energy transfer in N-isopropylacrylamide gel
Kajima Y., Yagi Y., Inomata H., Saito S.
Polymer Gels and Networks , 1993
110.
110
M. F. Shostakovskii
Dokl. Akad. Nauk SSSR , 1960
111.
111
M. Calvin
1956
113.
113
H. Blum
"Photodynamic Action and Diseases caused Light" , 1940
116.
HUANG X., UNNO H., AKEHATA T., HIRASA O.
Journal of Chemical Engineering of Japan , 2008
117.
HUANG X., UNNO H., AKEHATA T., HIRASA O.
Journal of Chemical Engineering of Japan , 1988
118.
HUANG X., UNNO H., AKEHATA T., HIRASA O.
Journal of Chemical Engineering of Japan , 1988
119.
Preparation and properties of soluble-insoluble immobilized proteases
Fujimura M., Mori T., Tosa T.
Biotechnology and Bioengineering , 1987
120.
120
V. V. Levchenko
Zhur. Obshch. Khim. , 1948
121.
Radical bulk polymerization of N-vinylcaprolactam
Solomon O.F., Corciovei M., Boghin˘ C.
Journal of Applied Polymer Science , 1968
122.
Properties of solutions of poly-N-vinylcaprolactam
Solomon O.F., Corciovei M., Ciută I., Boghină C.
Journal of Applied Polymer Science , 1968
123.
123
V. V. Levchenko
Zhur. Obshch. Khim. , 1952
124.
124
V. V. Levchenko
Zhur. Obshch. Khim. , 1952
125.
Lower critical solution temperature and hydrophobic hydration in aqueous polymer solutions
Tager A.A., Safronov A.P., Berezyuk E.A., Galaev I.Y.
Colloid and Polymer Science , 1994
126.
126
J. Wiemannand Ch. Clachet
Compt. rend. , 1948
127.
127
R. Pasternak
Helv. Chim. Acta , 1948
128.
Interaction between ethyl(hydroxyethyl)cellulose and sodium dodecyl sulphate in aqueous solution
Carlsson A., Karlstr�m G., Lindman B., Stenberg O.
Colloid and Polymer Science , 1988
131.
131
N. Thooi
Compt. rend. , 1958
132.
Application of temperature-induced phase partitioning at ambient temperature for enzyme purification.
Alred P.A., Kozlowski A., Harris J.M., Tjerneld F.
Journal of Chromatography A , 1994
133.
133
C. Wilson
Trans. Electrochem. Soc. , 1941
135.
Thermoreversible Gel Formation from Aqueous Aluminum Polyphosphate Solutions
de Oliveira Lima E.C., Galembeck F.
Journal of Colloid and Interface Science , 1994
136.
Poly(N-isopropylacrylamide) Latices Prepared with Sodium Dodecyl Sulfate
McPhee W., Tam K.C., Pelton R.
Journal of Colloid and Interface Science , 1993
137.
Preparation of aqueous latices with N-isopropylacrylamide
Pelton R.H., Chibante P.
Colloids and Surfaces , 1986
138.
The use of poly(N-isopropylacrylamide) latices as novel release systems
Snowden M.J.
Journal of the Chemical Society Chemical Communications , 1992
139.
Electrophoretic Mobility of Latex Particles Covered with Temperature-Sensitive Hydrogel Layers
Ohshima H., Makino K., Kato T., Fujimoto K., Kondo T., Kawaguchi H.
Journal of Colloid and Interface Science , 1993
140.
Surface Structure of Latex Particles Covered with Temperature-Sensitive Hydrogel Layers
Makino K., Yamamoto S., Fujimoto K., Kawaguchi H., Ohshima H.
Journal of Colloid and Interface Science , 1994
141.
Preparation of immobilized papain using thermosensitive latex particles
Kondo A., Imura K., Nakama K., Higashitani K.
Journal of Fermentation and Bioengineering , 1994
142.
Development and application of thermo-sensitive immunomicrospheres for antibody purification
Kondo A., Kaneko T., Higashitani K.
Biotechnology and Bioengineering , 1994
145.
Soap-Free Latices of Polyoxyethylene Chain-Binding Particles
Hoshino F., Sakai M., Kawaguchi H., Ohtsuka Y.
Polymer Journal , 1987
147.
147
Y. Sasada
Acta Cryst. , 1898
148.
The influence of chain length of a competitive polyanion and nature of monovalent counterions on the direction of the substitution reaction of polyelectrolyte complexes
149.
Enzymes in polyelectrolyte complexes. The effect of phase transition on thermal stability
MARGOLIN A.L., SHERSTYUK S.F., IZUMRUDOV V.A., ZEZIN A.B., KABANOV V.A.
FEBS Journal , 1985
150.
Preparation and properties of penicillin amidase immobilized in polyelectrolyte complexes.
Margolin A.L., Izumrudov V.A., švedas V.K., Zezin A.B., Kabanov V.A., Berezin I.V.
Biochimica et Biophysica Acta (BBA) - Enzymology , 1981
151.
Soluble-insoluble immobilized enzymes
Margolin A.L., Izumrudov V.A., ?vedas V.K., Zezin A.B.
Biotechnology and Bioengineering , 1982
153.
153
1899
154.
154
Friedl.
155.
155
M. V. Mal'tsev
Izv. Vys. Ucheb. Zaved., Tsvet. Met. , 1960
158.
Glucose‐responsive complex formation between poly(vinyl alcohol) and poly(N‐vinyl‐2‐pyrrolidone) with pendent phenylboronic acid moieties
159.
A polymer gel with electrically driven motility
Osada Y., Okuzaki H., Hori H.
Nature , 1992
160.
160
1912
161.
Concentration of large biomolecules with hydrogels
Vasheghani-Farahani E., Cooper D.G., Vera J.H., Weber M.E.
Chemical Engineering Science , 1992
162.
Concentration of macromolecules from aqueous solutions : a new swellex process
Badiger M.V., Kulkarni M.G., Mashelkar R.A.
Chemical Engineering Science , 1992
163.
Temperature sensitive gels as extraction solvents
Freitas R.F., Cussler E.L.
Chemical Engineering Science , 1987
164.
Chemical aspects of gel extraction
Gehrke S.H., Andrews G.P., Cussler E.L.
Chemical Engineering Science , 1986
165.
A Method for concentrating Solutes of High Molecular Weight
FLODIN P., GELOTTE B., PORATH J.
Nature , 1960
166.
166
1917
167.
Dewatering of biological slurry by using water‐absorbent polymer gel
Huang X., Akehata T., Unno H., Hirasa O.
Biotechnology and Bioengineering , 1989
168.
168
1918
169.
pH-Sensitive permeability control of polymer-grafted nylon capsule membranes
Okahata Y., Ozaki K., Seki T.
Journal of the Chemical Society Chemical Communications , 1984
170.
170
1918
172.
Insulin permeation through thermo-sensitive hydrogels
Bae Y.H., Okano T., Kim S.W.
Journal of Controlled Release , 1989
173.
173
Friedl.
174.
Permeation characteristics of porous glass and hydrogel composite membrane
Tsuji T., Otake K., Konno M., Saito S.
Journal of Applied Polymer Science , 1990
175.
OTAKE K., TSUJI T., KONNO M., SAITO S.
Journal of Chemical Engineering of Japan , 2008
177.
Affinity-precipitation using chitosan as ligand carrier
Senstad C., Mattiasson B.
Biotechnology and Bioengineering , 1989
179.
179
Chem. Abs. , 1947
182.
The synthesis of soluble polymer-ligand complexes for affinity precipitation studies
183.
Affinity precipitation of extracellular microbial enzymes
Pécs M., Eggert M., Schügerl K.
Journal of Biotechnology , 1991
184.
Production of cellobiose by enzymatic hydrolysis: Removal of ?-glucosidase from cellulase by affinity precipitation using chitosan
Homma T., Fujii M., Mori J., Kawakami T., Kuroda K., Taniguchi M.
Biotechnology and Bioengineering , 1993
185.
Purification of xylanase from Trichoderma viride by precipitation with an anionic polymer Eudragit S 100
Gupta M.N., Guoqiang D., Kaul R., Mattiasson B.
Biotechnology Techniques , 1994
186.
186
Chem. Abs. , 1956
187.
Purification of endo-polygalacturonase by affinity precipitation using alginate
Gupta M., Dong G., Mattiasson B.
Biotechnology and Applied Biochemistry , 1993
189.
189
M. Godchot
Bull. Soc. chim. France (5) , 1913
191.
191
M. Matsui
Mem. Coll. Sci., Kyoto Univ. , 1920
193.
193
E. Pannain
Gazzetta , 1909
197.
Soluble-insoluble enzyme catalysts
Charles M., Coughlin R.W., Hasselberger F.X.
Biotechnology and Bioengineering , 1974
199.
Preparation and properties of soluble-insoluble nicotinamide coenzymes
Coughlin R.W., Aizawa M., Charles M.
Biotechnology and Bioengineering , 1976
200.
200
Ref. Zh. Khim. , 1975
202.
Temperature-responsive graft copolymers for immobilization of enzymes
Takeuchi S., Omodaka I., Hasegawa K., Maeda Y., Kitano H.
Die Makromolekulare Chemie , 1993
203.
Microspheres prepared from temperature‐sensitive graft polymers
Kitano H., Yan C., Nakamura K.
Die Makromolekulare Chemie , 1991
204.
204
Cherkesov A I
Ref. Zh. Khim. , 1968
205.
205
N. Bunge
Zhur. Russ. Fiz.-Khim. Obshch. , 1889
206.
206
J. Petersen
Z. Phys. Chem. , 1900
207.
Hoshino K., Taniguchi M., Netsu Y., Fujii M.
Journal of Chemical Engineering of Japan , 2006
208.
Continuous ethanol production from raw starch using a reversibly soluble-autoprecipitating amylase and flocculating yeast cells
209.
209
C. J. Haggerty
Trans. Am. Electrochem. Soc. , 1929
210.
Immobilization of proteases in composite hydrogel based on poly(N-vinyl caprolactam)
Markvicheva E.A., Bronin A.S., Kudryavtseva N.E., Rumsh L.D., Kirsh Y.E., Zubov V.P.
Biotechnology Techniques , 1994
211.
211
C. Schall
Z. Elektrochem. , 1923
212.
A novel technique for entrapment of hybridoma cells in synthetic thermally reversible polymers
Markvicheva E.A., Kuz'kina I.F., Pashkin I.I., Plechko T.N., Kirsh Y.E., Zubov V.P.
Biotechnology Techniques , 1991
213.
Enzyme-exchangeable enzyme electrodes employing a thermoshrinking redox gel
Tatsuma T., Saito K., Oyama N.
Journal of the Chemical Society Chemical Communications , 1994
215.
Enzyme electrodes mediated by a thermoshrinking redox polymer
Tatsuma T., Saito K., Oyama N.
Analytical Chemistry , 1994
219.
Immobilization and characterization of ?-galactosidase in thermally reversible hydrogel beads
220.
Poly(vinyl methyl ether) gel for the construction of a thermosensitive immobilised enzyme system exhibiting controllable reaction initiation and termination
Kokufuta E., Ogane O., Ichijo H., Watanabe S., Hirasa O.
Journal of the Chemical Society Chemical Communications , 1992
221.
221
1960
223.
223
1959
224.
224
Chem. Abs. , 1959
225.
225
1960
226.
226
Chem. Abs. , 1961
228.
Photoinduced phase transition of gels
Mamada A., Tanaka T., Kungwatchakun D., Irie M.
Macromolecules , 1990
230.
Photoregulation of .alpha.-chymotrypsin by its immobilization in a photochromic azobenzene copolymer
Willner I., Rubin S., Zor T.
Journal of the American Chemical Society , 1991
234.
234
Ebach E A
Chem. Abs. , 1966
235.
Biochemically controlled thermal phase transition of gels
236.
Saccharide-sensitive phase transition of a lectin-loaded gel
238.
A novel immunoassay system and bioseparation process based on thermal phase separating polymers
239.
239
Mendelbaum H. G.
Bull. Soc. chim. France , 1973
240.
How do Specialty Polymers Modify the Chemical and Pharmaceutical Industries?
Belluš D.
Journal of Macromolecular Science - Pure and Applied Chemistry , 1994
241.
241
M. S. Kharasch
"Grignard Reactions of Nonmetallic Substances" , 1954
242.
Photoresponse of the release behavior of an organic compound by a azoaromatic polymer device
Ishihara K., Hamada N., Kato S., Shinohara I.
Journal of Polymer Science Polymer Chemistry Edition , 1984
244.
Consolvency of poly(N-isopropylacrylamide) in mixed water-methanol solutions: a look at spin-labeled polymers
Winnik F.M., Ottaviani M.F., Bossmann S.H., Garcia-Garibay M., Turro N.J.
Macromolecules , 1992
245.
Thermo-sensitive polymers as on-off switches for drug release
Bae Y.H., Okano T., Hsu R., Kim S.W.
Die Makromolekulare Chemie Rapid Communications , 1987
246.
Thermally on-off switching polymers for drug permeation and release
Okano T., Bae Y.H., Jacobs H., Kim S.W.
Journal of Controlled Release , 1990
247.
247
E. I. Levkoeva
Khim. Geterotsikl. Soed. , 1976
248.
248
M. Ya. Fioshin
Plasticheskie Massy , 1960
252.
Surface-modulated skin layers of thermal responsive hydrogels as on-off switches: II. Drug permeation
Yoshida R., Sakai K., Okano T., Sakurai Y.
Journal of Biomaterials Science, Polymer Edition , 1992
255.
Controlled release of amylase from a thermal and pH-sensitive, macroporous hydrogel
Liang-chang D., Qi Y., Hoffman A.S.
Journal of Controlled Release , 1992
256.
256
Z. V. Zvonkova
Zh. Strukt. Khim. , 1977
257.
Glucose-responsive insulin release from polymer capsule1
Ishihara K., Matsui K.
Journal of Polymer Science Part C Polymer Letters , 1986
258.
Controlled release of insulin from boronic acid gel under physiological conditions
Shiino D., Kataoka K., Koyama Y., Yokoyama M., Okano T., Sakura Y.
Journal of Controlled Release , 1994
259.
259
V. Elyutin
Trudy Moskov. Inst. Stali , 1939