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The synthesis and biological activity of 4-[bis(2-chloroethyl)amino]-DL-, L, and D-phenylalanine amides and peptides

Victor Pavlovich Krasnov 1
Victor Pavlovich Krasnov
, 
Elizaveta Aleksandrovna Zhdanova 1
Elizaveta Aleksandrovna Zhdanova
, 
Lyudmila Ivanovna Smirnova 2
Lyudmila Ivanovna Smirnova
1 Institute of Organic Synthesis, Ural Branch of Russian Academy of Sciences, Ekaterinburg
2 Cancer Research Center, Russian Academy of Medical Sciences, Moscow
10.1070/RC1995v064n11ABEH000193
Published 30 November 1994
Communication , Volume 64, Issue 11, 1049-1065
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Krasnov V. P., Zhdanova E. A., Smirnova L. I. The synthesis and biological activity of 4-[bis(2-chloroethyl)amino]-DL-, L, and D-phenylalanine amides and peptides // Russian Chemical Reviews. 1995. Vol. 64. No. 11. pp. 1049-1065.
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Krasnov V. P., Zhdanova E. A., Smirnova L. I. The synthesis and biological activity of 4-[bis(2-chloroethyl)amino]-DL-, L, and D-phenylalanine amides and peptides // Russian Chemical Reviews. 1995. Vol. 64. No. 11. pp. 1049-1065.
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TY - JOUR
DO - 10.1070/RC1995v064n11ABEH000193
UR - https://rcr.colab.ws/publications/10.1070/RC1995v064n11ABEH000193
TI - The synthesis and biological activity of 4-[bis(2-chloroethyl)amino]-DL-, L, and D-phenylalanine amides and peptides
T2 - Russian Chemical Reviews
AU - Krasnov, Victor Pavlovich
AU - Zhdanova, Elizaveta Aleksandrovna
AU - Smirnova, Lyudmila Ivanovna
PY - 1995
DA - 1994/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 1049-1065
IS - 11
VL - 64
ER -
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@article{1995_Krasnov,
author = {Victor Pavlovich Krasnov and Elizaveta Aleksandrovna Zhdanova and Lyudmila Ivanovna Smirnova},
title = {The synthesis and biological activity of 4-[bis(2-chloroethyl)amino]-DL-, L, and D-phenylalanine amides and peptides},
journal = {Russian Chemical Reviews},
year = {1995},
volume = {64},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RC1995v064n11ABEH000193},
number = {11},
pages = {1049--1065},
doi = {10.1070/RC1995v064n11ABEH000193}
}
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Krasnov, Victor Pavlovich, et al. “The synthesis and biological activity of 4-[bis(2-chloroethyl)amino]-DL-, L, and D-phenylalanine amides and peptides.” Russian Chemical Reviews, vol. 64, no. 11, Nov. 1995, pp. 1049-1065. https://rcr.colab.ws/publications/10.1070/RC1995v064n11ABEH000193.
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Abstract

The review is devoted to the synthesis and biological properties of the amides and peptides containing the stereoisomers of 4-[bis(2-chloroethyl)amino]phenylalanine. The approaches to the selection of the structures of the compounds indicated, ensuring an increase in the selectivity of their antitumour activity, are examined. The bibliography includes 131 references.

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