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C-Alkenylation of pyrimidine nucleosides and their analogues

Anatolii Fedorovich Nasonov 1
Anatolii Fedorovich Nasonov
, 
Galina Anatol'evna Korshunova 2
Galina Anatol'evna Korshunova
1 M. V. Lomonosov Moscow State University, Department of Chemistry
2 A. N. Belozersky Institute of Physico-Chemical Biology, Moscow
10.1070/RC1999v068n06ABEH000466
Published 30 November 1998
Communication , Volume 68, Issue 6, 483-504
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Nasonov A. F., Korshunova G. A. C-Alkenylation of pyrimidine nucleosides and their analogues // Russian Chemical Reviews. 1999. Vol. 68. No. 6. pp. 483-504.
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Nasonov A. F., Korshunova G. A. C-Alkenylation of pyrimidine nucleosides and their analogues // Russian Chemical Reviews. 1999. Vol. 68. No. 6. pp. 483-504.
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TY - JOUR
DO - 10.1070/RC1999v068n06ABEH000466
UR - https://rcr.colab.ws/publications/10.1070/RC1999v068n06ABEH000466
TI - C-Alkenylation of pyrimidine nucleosides and their analogues
T2 - Russian Chemical Reviews
AU - Nasonov, Anatolii Fedorovich
AU - Korshunova, Galina Anatol'evna
PY - 1999
DA - 1998/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 483-504
IS - 6
VL - 68
ER -
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@article{1999_Nasonov,
author = {Anatolii Fedorovich Nasonov and Galina Anatol'evna Korshunova},
title = {C-Alkenylation of pyrimidine nucleosides and their analogues},
journal = {Russian Chemical Reviews},
year = {1999},
volume = {68},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RC1999v068n06ABEH000466},
number = {6},
pages = {483--504},
doi = {10.1070/RC1999v068n06ABEH000466}
}
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Nasonov, Anatolii Fedorovich, and Galina Anatol'evna Korshunova. “C-Alkenylation of pyrimidine nucleosides and their analogues.” Russian Chemical Reviews, vol. 68, no. 6, Nov. 1999, pp. 483-504. https://rcr.colab.ws/publications/10.1070/RC1999v068n06ABEH000466.
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Abstract

Methods for C-alkenylation of heterocycle moieties of pyrimidine nucleosides and their analogues are generalised. The methods employing both organoelement nucleoside derivatives (organomercury, -tin, -boron and -lithium) and organoelement alkene derivatives (organomagnesium, -boron, -aluminium, -tin and -silicon) as well as palladium-catalysed oxidative coupling and photochemical reactions are considered. The reaction conditions (the role of solvents, catalysts and co-catalysts, temperature and time modes) are discussed. The advantages and the drawbacks of different approaches for introduction of alkenyl groups are discussed. Examples of practical applications of alkenylated nucleoside derivatives and their analogues are given. The bibliography includes 92 references.

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