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HIV-1 integrase inhibitors as new components of antiviral therapy

Tat'yana Aleksandrovna Prikazchikova 1
Tat'yana Aleksandrovna Prikazchikova
, 
Anna Maksimovna Sycheva 2
Anna Maksimovna Sycheva
, 
Yulia Yur'evna Agapkina 2
Yulia Yur'evna Agapkina
, 
Dmitrii Andreevich Aleksandrov 1
Dmitrii Andreevich Aleksandrov
, 
Marina Borisovna Gottikh 1
Marina Borisovna Gottikh
1 Lomonosov Moscow State University, Belozersky Research Institute of Physico-Chemical Biology
2 Lomonosov Moscow State University, Faculty of Chemistry
Published 30 November 2007
Communication , Volume 77, Issue 5, 421-434
8
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Prikazchikova T. A. et al. HIV-1 integrase inhibitors as new components of antiviral therapy // Russian Chemical Reviews. 2008. Vol. 77. No. 5. pp. 421-434.
GOST all authors (up to 50)
Prikazchikova T. A., Sycheva A. M., Agapkina Y. Y., Aleksandrov D. A., Gottikh M. B. HIV-1 integrase inhibitors as new components of antiviral therapy // Russian Chemical Reviews. 2008. Vol. 77. No. 5. pp. 421-434.
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TY - JOUR
DO - 10.1070/RC2008v077n05ABEH003779
UR - https://rcr.colab.ws/publications/10.1070/RC2008v077n05ABEH003779
TI - HIV-1 integrase inhibitors as new components of antiviral therapy
T2 - Russian Chemical Reviews
AU - Prikazchikova, Tat'yana Aleksandrovna
AU - Sycheva, Anna Maksimovna
AU - Agapkina, Yulia Yur'evna
AU - Aleksandrov, Dmitrii Andreevich
AU - Gottikh, Marina Borisovna
PY - 2008
DA - 2007/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 421-434
IS - 5
VL - 77
ER -
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@article{2008_Prikazchikova,
author = {Tat'yana Aleksandrovna Prikazchikova and Anna Maksimovna Sycheva and Yulia Yur'evna Agapkina and Dmitrii Andreevich Aleksandrov and Marina Borisovna Gottikh},
title = {HIV-1 integrase inhibitors as new components of antiviral therapy},
journal = {Russian Chemical Reviews},
year = {2008},
volume = {77},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RC2008v077n05ABEH003779},
number = {5},
pages = {421--434},
doi = {10.1070/RC2008v077n05ABEH003779}
}
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Prikazchikova, Tat'yana Aleksandrovna, et al. “HIV-1 integrase inhibitors as new components of antiviral therapy.” Russian Chemical Reviews, vol. 77, no. 5, Nov. 2008, pp. 421-434. https://rcr.colab.ws/publications/10.1070/RC2008v077n05ABEH003779.
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Abstract

Structural and functional features of HIV-1 integrase are considered and the state of the art in the quest for effective inhibitors of this enzyme is reported. The major classes of integrase inhibitors with known mechanisms of action as well as their in vitro and in vivo inhibitory activities are presented.