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Synthesis and applications of 2-aminopyrimidine derivatives as key intermediates in chemical synthesis of biomolecules

Elena Vadimovna Koroleva 1
Elena Vadimovna Koroleva
, 
Klaudiya Nikolaevna Gusak 1
Klaudiya Nikolaevna Gusak
, 
Zhanna Vladimirovna Ignatovich 1
Zhanna Vladimirovna Ignatovich
1 Institute of Chemistry of New Materials of the National Academy of Sciences of Belarus
10.1070/RC2010v079n08ABEH004116
Published 30 November 2009
Communication , Volume 79, Issue 8, 655-681
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Koroleva E. V., Gusak K. N., Ignatovich Z. V. Synthesis and applications of 2-aminopyrimidine derivatives as key intermediates in chemical synthesis of biomolecules // Russian Chemical Reviews. 2010. Vol. 79. No. 8. pp. 655-681.
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Koroleva E. V., Gusak K. N., Ignatovich Z. V. Synthesis and applications of 2-aminopyrimidine derivatives as key intermediates in chemical synthesis of biomolecules // Russian Chemical Reviews. 2010. Vol. 79. No. 8. pp. 655-681.
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TY - JOUR
DO - 10.1070/RC2010v079n08ABEH004116
UR - https://rcr.colab.ws/publications/10.1070/RC2010v079n08ABEH004116
TI - Synthesis and applications of 2-aminopyrimidine derivatives as key intermediates in chemical synthesis of biomolecules
T2 - Russian Chemical Reviews
AU - Koroleva, Elena Vadimovna
AU - Gusak, Klaudiya Nikolaevna
AU - Ignatovich, Zhanna Vladimirovna
PY - 2010
DA - 2009/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 655-681
IS - 8
VL - 79
ER -
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@article{2010_Koroleva,
author = {Elena Vadimovna Koroleva and Klaudiya Nikolaevna Gusak and Zhanna Vladimirovna Ignatovich},
title = {Synthesis and applications of 2-aminopyrimidine derivatives as key intermediates in chemical synthesis of biomolecules},
journal = {Russian Chemical Reviews},
year = {2010},
volume = {79},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RC2010v079n08ABEH004116},
number = {8},
pages = {655--681},
doi = {10.1070/RC2010v079n08ABEH004116}
}
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Koroleva, Elena Vadimovna, et al. “Synthesis and applications of 2-aminopyrimidine derivatives as key intermediates in chemical synthesis of biomolecules.” Russian Chemical Reviews, vol. 79, no. 8, Nov. 2010, pp. 655-681. https://rcr.colab.ws/publications/10.1070/RC2010v079n08ABEH004116.
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Abstract

Published data on the main approaches to the formation of the heterocyclic 2-aminopyrimidine system, which is one of important pharmacophores responsible for the biological properties of its derivatives, are described systematically. Main chemical transformations of functionalized 2-aminopyrimidines and their application in the synthesis of modern pharmaceuticals are considered.