Home / Articles / Advances in the synthesis of imidazo[1,5-\textit{a}]- and imidazo[1,2-\textit{a}]quinoxalines

Advances in the synthesis of imidazo[1,5-\textit{a}]- and imidazo[1,2-\textit{a}]quinoxalines

Vakhid Abdulla-ogly Mamedov 1
Vakhid Abdulla-ogly Mamedov
, 
Aleksei Aleksandrovich Kalinin 1
Aleksei Aleksandrovich Kalinin
1 A. E. Arbuzov Institute of Organic and Physical Chemistry of Kazan Scientific Center of Russian Academy of Sciences, Kazan
10.1070/RC2014v083n09ABEH004424
Published 30 November 2013
Communication , Volume 83, Issue 9, 820-847
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Mamedov V. A., Kalinin A. A. Advances in the synthesis of imidazo[1,5-\textit{a}]- and imidazo[1,2-\textit{a}]quinoxalines // Russian Chemical Reviews. 2014. Vol. 83. No. 9. pp. 820-847.
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Mamedov V. A., Kalinin A. A. Advances in the synthesis of imidazo[1,5-\textit{a}]- and imidazo[1,2-\textit{a}]quinoxalines // Russian Chemical Reviews. 2014. Vol. 83. No. 9. pp. 820-847.
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TY - JOUR
DO - 10.1070/RC2014v083n09ABEH004424
UR - https://rcr.colab.ws/publications/10.1070/RC2014v083n09ABEH004424
TI - Advances in the synthesis of imidazo[1,5-\textit{a}]- and imidazo[1,2-\textit{a}]quinoxalines
T2 - Russian Chemical Reviews
AU - Mamedov, Vakhid Abdulla-ogly
AU - Kalinin, Aleksei Aleksandrovich
PY - 2014
DA - 2013/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 820-847
IS - 9
VL - 83
ER -
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@article{2014_Mamedov,
author = {Vakhid Abdulla-ogly Mamedov and Aleksei Aleksandrovich Kalinin},
title = {Advances in the synthesis of imidazo[1,5-\textit{a}]- and imidazo[1,2-\textit{a}]quinoxalines},
journal = {Russian Chemical Reviews},
year = {2014},
volume = {83},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RC2014v083n09ABEH004424},
number = {9},
pages = {820--847},
doi = {10.1070/RC2014v083n09ABEH004424}
}
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Mamedov, Vakhid Abdulla-ogly, and Aleksei Aleksandrovich Kalinin. “Advances in the synthesis of imidazo[1,5-\textit{a}]- and imidazo[1,2-\textit{a}]quinoxalines.” Russian Chemical Reviews, vol. 83, no. 9, Nov. 2014, pp. 820-847. https://rcr.colab.ws/publications/10.1070/RC2014v083n09ABEH004424.
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Abstract

This review is intended to generalize and systematize available information on the synthesis of imidazo[1,5-\textit{a}]- and imidazo[1,2-\textit{a}]quinoxalines. Relevant studies published in the last 10--15 years, as well as earlier studies less familiar to the broad chemical community, are surveyed. Major methods of formation of the imidazoquinoxaline system from substituted quinoxalines and imidazoles according to the type of bond being formed are presented. Special focus is placed on the radically new methods that enable the synthesis of various derivatives of these heterocyclic systems from available and inexpensive reagents. The mechanisms of formation of these compounds are discussed. Information on the biological activity of imidazo[1,5-\textit{a}]- and imidazo[1,2-\textit{a}]quinoxalines and examples of pharmaceuticals based on them are reported.

The bibliography includes 179 references.

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