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Polyalkoxyflavonoids as inhibitors of cell division

Victor Vladimirovich Semenov 1
Victor Vladimirovich Semenov
, 
M N Semenova 2
M N Semenova
1 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow
2 Koltzov Institute of Developmental Biology, Russian Academy of Sciences, Moscow
10.1070/RCR4449
Published 30 November 2014
Communication , Volume 84, Issue 2, 134-158
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Semenov V. V., Semenova M. N. Polyalkoxyflavonoids as inhibitors of cell division // Russian Chemical Reviews. 2015. Vol. 84. No. 2. pp. 134-158.
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Semenov V. V., Semenova M. N. Polyalkoxyflavonoids as inhibitors of cell division // Russian Chemical Reviews. 2015. Vol. 84. No. 2. pp. 134-158.
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TY - JOUR
DO - 10.1070/RCR4449
UR - https://rcr.colab.ws/publications/10.1070/RCR4449
TI - Polyalkoxyflavonoids as inhibitors of cell division
T2 - Russian Chemical Reviews
AU - Semenov, Victor Vladimirovich
AU - Semenova, M N
PY - 2015
DA - 2014/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 134-158
IS - 2
VL - 84
ER -
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@article{2015_Semenov,
author = {Victor Vladimirovich Semenov and M N Semenova},
title = {Polyalkoxyflavonoids as inhibitors of cell division},
journal = {Russian Chemical Reviews},
year = {2015},
volume = {84},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RCR4449},
number = {2},
pages = {134--158},
doi = {10.1070/RCR4449}
}
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Semenov, Victor Vladimirovich, and M N Semenova. “Polyalkoxyflavonoids as inhibitors of cell division.” Russian Chemical Reviews, vol. 84, no. 2, Nov. 2015, pp. 134-158. https://rcr.colab.ws/publications/10.1070/RCR4449.
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Abstract

Being structural analogues of natural microtubule-destabilizing cytostatics, polyalkoxyflavonoids represent a promising class of compounds for anticancer drug design. The review covers synthetic routes to various polyalkoxyflavonoids and the results of biological assays in vitro on human cancer cells and \it{in vivo} using sea urchin embryos as a model. Mechanisms of action and structure--relationship activity for polyalkoxyflavonoids are discussed.

The bibliography includes 151 references.

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