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New approaches to targeted drug delivery to tumour cells

Evgeniy Sergeyevich Severin 1
Evgeniy Sergeyevich Severin
1 Russian Research Center of Molecular Diagnostics and Therapy, Moscow, Russian Federation
10.1070/RCR4468
Published 30 November 2014
Communication , Volume 84, Issue 1, 43-60
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Severin E. S. New approaches to targeted drug delivery to tumour cells // Russian Chemical Reviews. 2015. Vol. 84. No. 1. pp. 43-60.
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Severin E. S. New approaches to targeted drug delivery to tumour cells // Russian Chemical Reviews. 2015. Vol. 84. No. 1. pp. 43-60.
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TY - JOUR
DO - 10.1070/RCR4468
UR - https://rcr.colab.ws/publications/10.1070/RCR4468
TI - New approaches to targeted drug delivery to tumour cells
T2 - Russian Chemical Reviews
AU - Severin, Evgeniy Sergeyevich
PY - 2015
DA - 2014/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 43-60
IS - 1
VL - 84
ER -
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@article{2015_Severin,
author = {Evgeniy Sergeyevich Severin},
title = {New approaches to targeted drug delivery to tumour cells},
journal = {Russian Chemical Reviews},
year = {2015},
volume = {84},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RCR4468},
number = {1},
pages = {43--60},
doi = {10.1070/RCR4468}
}
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Severin, Evgeniy Sergeyevich. “New approaches to targeted drug delivery to tumour cells.” Russian Chemical Reviews, vol. 84, no. 1, Nov. 2015, pp. 43-60. https://rcr.colab.ws/publications/10.1070/RCR4468.
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Abstract

Basic approaches to the design of targeted drugs for the treatment of human malignant tumours have been considered. The stages of the development of these approaches have been described in detail and theoretically substantiated, and basic experimental results have been reported. Considerable attention is paid to the general characteristic of nanopharmacological drugs and to the description of mechanisms of cellular interactions with nanodrugs. The potentialities and limitations of application of nanodrugs for cancer therapy and treatment of other diseases have been considered. The use of nanodrugs conjugated with vector molecules seems to be the most promising trend of targeted therapy of malignant tumours.

The bibliography includes 122 references.

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