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Biomedical applications of capillary electrophoresis

Lyudmila Alekseevna Kartsova 1
Lyudmila Alekseevna Kartsova
, 
Elena Andreevna Bessonova 1
Elena Andreevna Bessonova
1 Institute of Chemistry, St. Petersburg State University
10.1070/RCR4492
Published 30 November 2014
Communication , Volume 84, Issue 8, 860-874
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Kartsova L. A., Bessonova E. A. Biomedical applications of capillary electrophoresis // Russian Chemical Reviews. 2015. Vol. 84. No. 8. pp. 860-874.
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Kartsova L. A., Bessonova E. A. Biomedical applications of capillary electrophoresis // Russian Chemical Reviews. 2015. Vol. 84. No. 8. pp. 860-874.
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TY - JOUR
DO - 10.1070/RCR4492
UR - https://rcr.colab.ws/publications/10.1070/RCR4492
TI - Biomedical applications of capillary electrophoresis
T2 - Russian Chemical Reviews
AU - Kartsova, Lyudmila Alekseevna
AU - Bessonova, Elena Andreevna
PY - 2015
DA - 2014/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 860-874
IS - 8
VL - 84
ER -
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@article{2015_Kartsova,
author = {Lyudmila Alekseevna Kartsova and Elena Andreevna Bessonova},
title = {Biomedical applications of capillary electrophoresis},
journal = {Russian Chemical Reviews},
year = {2015},
volume = {84},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RCR4492},
number = {8},
pages = {860--874},
doi = {10.1070/RCR4492}
}
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Kartsova, Lyudmila Alekseevna, and Elena Andreevna Bessonova. “Biomedical applications of capillary electrophoresis.” Russian Chemical Reviews, vol. 84, no. 8, Nov. 2015, pp. 860-874. https://rcr.colab.ws/publications/10.1070/RCR4492.
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Abstract

The review deals with modern analytical approaches used in capillary electrophoresis for solving medical and biological problems: search for biomarkers of various diseases and rapid diagnosis based on characteristic profiles of biologically active compounds by capillary electrophoresis with mass spectrometric detection; monitoring of the residual drugs in biological fluids for evaluating the efficiency of drug therapy; testing of the enantiomeric purity of pharmaceutical products; the use of novel materials as components of stationary and pseudo-stationary phases in capillary electrophoresis and capillary electrochromatography to increase the selectivity of separation of components of complex matrices; and identification of various on-line preconcentration techniques to reduce the detection limits of biologically active analytes. A~topical trend in capillary electrophoresis required in clinical practice, viz., the design of microfluidic systems, is discussed.

The bibliography includes 173~references.

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