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Synthesis and properties of 2-mono- and 2,3-disubstituted thiochromones

Vyacheslav Yakovlevich Sosnovskikh 1
Vyacheslav Yakovlevich Sosnovskikh
1 Institute of Natural Sciences and Mathematics, Ural Federal University named after the First President of Russia B. N. Yeltsin
10.1070/RCR4756
Published 30 November 2017
Review , RCR4756, Volume 87, Issue 1, 49-88
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Sosnovskikh V. Y. Synthesis and properties of 2-mono- and 2,3-disubstituted thiochromones // Russian Chemical Reviews. 2017. Vol. 87. No. 1. pp. 49-88.
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Sosnovskikh V. Y. Synthesis and properties of 2-mono- and 2,3-disubstituted thiochromones // Russian Chemical Reviews. 2017. Vol. 87. No. 1. pp. 49-88.
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TY - JOUR
DO - 10.1070/RCR4756
UR - https://rcr.colab.ws/publications/10.1070/RCR4756
TI - Synthesis and properties of 2-mono- and 2,3-disubstituted thiochromones
T2 - Russian Chemical Reviews
AU - Sosnovskikh, Vyacheslav Yakovlevich
PY - 2017
DA - 2017/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 49-88
IS - 1
VL - 87
ER -
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@article{2017_Sosnovskikh,
author = {Vyacheslav Yakovlevich Sosnovskikh},
title = {Synthesis and properties of 2-mono- and 2,3-disubstituted thiochromones},
journal = {Russian Chemical Reviews},
year = {2017},
volume = {87},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RCR4756},
number = {1},
pages = {49--88},
doi = {10.1070/RCR4756}
}
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Sosnovskikh, Vyacheslav Yakovlevich. “Synthesis and properties of 2-mono- and 2,3-disubstituted thiochromones.” Russian Chemical Reviews, vol. 87, no. 1, Nov. 2017, pp. 49-88. https://rcr.colab.ws/publications/10.1070/RCR4756.
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Abstract

Data on the methods of synthesis, chemical reactivity and biological activity of 2-mono- and 2,3-disubstituted thiochromones are integrated and described systematically. Particular sections of the review address 2-arylthiochromones (thioflavones), 2-alkyl- and 2,3-dialkyl-substituted thiochromones and functionalized thiochromones with electron-donating (amino, hydroxy or mercapto group) or electron-withdrawing (cyano, nitro, formyl or carboxyl group or halogen atom) groups in positions 2 and/or 3. Analysis of published data indicates that chemical transformations of thiochromones, including functional derivatives, are rarely accompanied by thiopyrone ring opening, which distinguishes these compounds from representatives of the chromone system. Reaction conditions and product yields and data on the biological activities of some compounds of this class are given.

The bibliography includes 189 references.

Funders

Russian Foundation for Basic Research
17-03-00340

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