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Purine derivatives with antituberculosis activity

Dmitry Andreevich Gruzdev 1
Dmitry Andreevich Gruzdev
, 
Vera Vasil'evna Musiyak 1
Vera Vasil'evna Musiyak
, 
Galina L'vovna Levit 1
Galina L'vovna Levit
, 
Victor Pavlovich Krasnov 1
Victor Pavlovich Krasnov
, 
1 I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of Russian Academy of Sciences, Ekaterinburg
10.1070/RCR4772
Published 30 November 2017
Review , RCR4772, Volume 87, Issue 6, 604-618
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Gruzdev D. A. et al. Purine derivatives with antituberculosis activity // Russian Chemical Reviews. 2017. Vol. 87. No. 6. pp. 604-618.
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Gruzdev D. A., Musiyak V. V., Levit G. L., Krasnov V. P., Charushin V. N. Purine derivatives with antituberculosis activity // Russian Chemical Reviews. 2017. Vol. 87. No. 6. pp. 604-618.
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TY - JOUR
DO - 10.1070/RCR4772
UR - https://rcr.colab.ws/publications/10.1070/RCR4772
TI - Purine derivatives with antituberculosis activity
T2 - Russian Chemical Reviews
AU - Gruzdev, Dmitry Andreevich
AU - Musiyak, Vera Vasil'evna
AU - Levit, Galina L'vovna
AU - Krasnov, Victor Pavlovich
AU - Charushin, Valery Nikolaevich
PY - 2017
DA - 2017/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 604-618
IS - 6
VL - 87
ER -
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@article{2017_Gruzdev,
author = {Dmitry Andreevich Gruzdev and Vera Vasil'evna Musiyak and Galina L'vovna Levit and Victor Pavlovich Krasnov and Valery Nikolaevich Charushin},
title = {Purine derivatives with antituberculosis activity},
journal = {Russian Chemical Reviews},
year = {2017},
volume = {87},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RCR4772},
number = {6},
pages = {604--618},
doi = {10.1070/RCR4772}
}
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Gruzdev, Dmitry Andreevich, et al. “Purine derivatives with antituberculosis activity.” Russian Chemical Reviews, vol. 87, no. 6, Nov. 2017, pp. 604-618. https://rcr.colab.ws/publications/10.1070/RCR4772.
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Abstract

The review summarizes the data published over the last 10--15 years concerning the key groups of purine derivatives with antituberculosis activity. The structures of purines containing heteroatoms (S, O, N), fragments of heterocycles, amino acids and peptides, in the 6-position, as well as of purine nucleosides are presented. The possible targets for the action of such compounds and structure--activity relationship are discussed. Particular attention is paid to the most active compounds, which are of considerable interest as a basis for the development of efficient antituberculosis drugs.

The bibliography includes 99 references.

Funders

Russian Science Foundation
14-13-01077

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