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Recent advances in the chemistry of pyridazine --- an important representative of six-membered nitrogen heterocycles

Pavel Gennad'evich Sergeev 1
Pavel Gennad'evich Sergeev
, 
Valentin Georgievich Nenajdenko 1
Valentin Georgievich Nenajdenko
1 Lomonosov Moscow State University, Faculty of Chemistry
10.1070/RCR4922
Published 30 November 2019
Review , RCR4922, Volume 89, Issue 4, 393-429
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Sergeev P. G., Nenajdenko V. G. Recent advances in the chemistry of pyridazine --- an important representative of six-membered nitrogen heterocycles // Russian Chemical Reviews. 2019. Vol. 89. No. 4. pp. 393-429.
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Sergeev P. G., Nenajdenko V. G. Recent advances in the chemistry of pyridazine --- an important representative of six-membered nitrogen heterocycles // Russian Chemical Reviews. 2019. Vol. 89. No. 4. pp. 393-429.
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TY - JOUR
DO - 10.1070/RCR4922
UR - https://rcr.colab.ws/publications/10.1070/RCR4922
TI - Recent advances in the chemistry of pyridazine --- an important representative of six-membered nitrogen heterocycles
T2 - Russian Chemical Reviews
AU - Sergeev, Pavel Gennad'evich
AU - Nenajdenko, Valentin Georgievich
PY - 2019
DA - 2019/11/30
PB - ANO Editorial Board of the journal Uspekhi Khimii
SP - 393-429
IS - 4
VL - 89
ER -
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@article{2019_Sergeev,
author = {Pavel Gennad'evich Sergeev and Valentin Georgievich Nenajdenko},
title = {Recent advances in the chemistry of pyridazine --- an important representative of six-membered nitrogen heterocycles},
journal = {Russian Chemical Reviews},
year = {2019},
volume = {89},
publisher = {ANO Editorial Board of the journal Uspekhi Khimii},
month = {Nov},
url = {https://rcr.colab.ws/publications/10.1070/RCR4922},
number = {4},
pages = {393--429},
doi = {10.1070/RCR4922}
}
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Sergeev, Pavel Gennad'evich, and Valentin Georgievich Nenajdenko. “Recent advances in the chemistry of pyridazine --- an important representative of six-membered nitrogen heterocycles.” Russian Chemical Reviews, vol. 89, no. 4, Nov. 2019, pp. 393-429. https://rcr.colab.ws/publications/10.1070/RCR4922.
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Keywords

diazines
pyridazines
synthesis of nitrogen-containing heterocycles

Abstract

The review is devoted to recent advances in the chemistry of pyridazine --- a six-membered heterocycle containing two nitrogen atoms in adjacent positions. The practical significance of title compounds is demonstrated and published data of the last decade devoted to them are considered systematically. The modern synthetic approaches to pyridazine derivatives are described in detail, analyzed and classified according to the precursor molecules involved in ring closure. The chemical properties of pyridazines are considered, including both reactions of the diazine ring and reactions of various substituents attached to the ring. Particular attention is given to the application of some pyridazine derivatives as pharmaceuticals, optical materials and ligands for catalysis.

The bibliography includes 180 references.

Funders

Russian Foundation for Basic Research
16-29-10669

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